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U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen

Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0880-8

Abstract: Estrogen regulates miRNA expression in a typical U-shaped dose-response pattern.Nonmonotonic dose-response in prostate could be a component of estrogen signature.doses of estradiol (0.2 and 2 mg·kg ), and whose expression returned to the control level at a larger doseindicate that the prostate is a reliable organ for evaluating estrogenic activity and that the typical nonmonotonicdose-response relationship could be used as a novel biomarker for estrogenicity.

Keywords： miRNA     Prostate     Estradiol     Nonmonotonic dose-response     Estrogenicity     Drosha    

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Low-dose CT for lung cancer screening: opportunities and challenges

Hongbing Shen

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 116-121 doi: 10.1007/s11684-017-0600-1

Abstract: However, minimal progress was achieved until recently, when low-dose spiral computed tomography (LDCT

Keywords： lung cancer     low-dose computerized tomography     early detection     opportunities     challenges    

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Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the

Yue’e Dai, Dongxu Lei, Zhenghua Huang, Yan Yin, G. Allen Finley, Yunxia Zuo

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 288-295 doi: 10.1007/s11684-012-0208-4

Abstract: In each phase, 24 participants were allocated a different tramadol dose.In phase 1, seven dose levels were used within the range 0.1–0.4 mg?Phase 1 was insufficient to identify the MED, and we increased the dose to 0.4–0.8 mg?In phase 2, it was 84.7% (95% CI, 0.789–0.991) with the dose 0.8 mg?kg-1?In phase 3, the successful analgesia probability for dose 0.35 mg?kg-1?

Keywords： tramadol     minimum effective dose     postoperative analgesia     infants     continual reassessment method    

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Comparison of exogenous degrader-enhanced bioremediation with low-dose persulfate oxidation for polycyclic

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 11, doi: 10.1007/s11783-023-1733-x

Abstract: In this study, bioaugmentation with a PAH-degrading Bacillus PheN7 (BA) and low-dose persulfate

Keywords： Bioaugmentation     Low-dose persulfate oxidation     Polycyclic aromatic hydrocarbon     Remediation    

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Early assessment of the safety and immunogenicity of a third dose (booster) of COVID-19 immunization

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 93-101 doi: 10.1007/s11684-021-0914-x

Abstract: Here we report a pilot open-label trial of a third dose of BBIBP-CorV, an inactivated SARS-CoV-2 vaccinein all participants within 4 weeks, surpassing the peak antibody titers elicited by the initial two-dose

Keywords： COVID-19     SARS-CoV-2     vaccine     immunization     booster immunization    

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An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 506-509 doi: 10.1007/s11684-013-0294-y

Abstract:

This study aimed to investigate patient dose in diagnostic screen-film radiographic examinations in

Keywords： radiation dosage     radiology     radiation protection     radiography/statistics & numerical data    

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Effect of chemical dose on phosphorus removal and membrane fouling control in a UCT-MBR

Guangrong Sun, Chuanyi Zhang, Wei Li, Limei Yuan, Shilong He, Liping Wang

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 1, doi: 10.1007/s11783-019-1085-8

Abstract: To enhance phosphorus removal and make the effluent meet the strict discharge level of total phosphorus (TP, 0.5 mg/L), flocculant dosing is frequently applied. In this study, the performance of aluminum sulfate dosing in a University of Cape Town Membrane Bioreactor (UCT-MBR) was investigated, in terms of the nutrients removal performance, sludge characteristics and membrane fouling. The results indicated that the addition of aluminum sulfate into the aerobic reactor continuously had significantly enhanced phosphorus removal. Moreover, COD, NH -N and TN removal were not affected and effluent all met the first level A criteria of GB18918-2002. In addition, the addition of aluminum sulfate had improved the sludge activity slightly and reduced trans-membrane pressure (TMP) increase rate from 1.13 KPa/d to 0.57 KPa/d effectively. The membrane fouling was alleviated attributed to the increased average particle sizes and the decreased accumulation of the small sludge particles on membrane surface. Furthermore, the decline of extracellular polymeric substance (EPS) concentration in mixed sludge liquid decreased its accumulation on membrane surface, resulting in the mitigation of membrane fouling directly.

Keywords： University of Cape Town Bioreactor (UCT-MBR)     enhanced nutrients removal     aluminum sulfate     sludge activity     membrane fouling    

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radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes from an open-label, dose-escalation

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 231-239 doi: 10.1007/s11684-022-0939-9

Abstract: neoadjuvant radiohormonal therapy for oligometastatic prostate cancer (OMPC), we conducted a 3 + 3 dosewas treatment-related toxicities and adverse events; secondary outcomes were radiological treatment response

Keywords： neoadjuvant     radiotherapy     oligometastatic     prostate cancer     radical prostatectomy    

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Cancer and the environment: Filling knowledge gaps together

Linda S. BIRNBAUM PhD, DABT, ATS,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 131-133 doi: 10.1007/s11684-010-0044-3

Abstract: . “Low dose” is also another consideration.We need to understand the biological effect of low dose exposure and we should clearly define what theymean by low dose research.For example, are we measuring the administered dose, or the internal/circulating dose?

Keywords： environment     genes     environmental exposure     environmental agent     persistence     chemicals     inert ingredients     low dose    

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Venetoclax and low-dose cytarabine induced complete remission in a patient with high-risk acute myeloid

Bingshan Liu, Roshni Narurkar, Madhura Hanmantgad, Wahib Zafar, Yongping Song, Delong Liu

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 593-599 doi: 10.1007/s11684-018-0635-y

Abstract: The patient with high risk AML achieved complete response to the combined treatment regimen of low-dose

Keywords： venetoclax     cytarabine     AML     leukemia    

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Efficient scheme of low-dose CT reconstruction using TV minimization with an adaptive stopping strategy Article

Yong DING, Tuo HU

Frontiers of Information Technology & Electronic Engineering 2017, Volume 18, Issue 12,   Pages 2001-2008 doi: 10.1631/FITEE.1700287

Abstract: Recently, low-dose computed tomography (CT) has become highly desirable because of the growing concernFor low-dose CT imaging, it is a significant challenge to guarantee image quality while reducing radiationTo promote low-dose CT imaging, we propose a promising reconstruction scheme which combines total-variationmethods in terms of image quality and computational efficiency, which validates its potential for low-dose

Keywords： Low-dose computed tomography (CT)     CT imaging     Total variation     Sparse dictionary learning    

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The lethal dose test of Ginsenoside CK and Icraiin for sperm in vitro

Yu Hongliang,Chang Mingxiu,Cao Henghai,Bo Liwei,Yang Yongjun,Li Chongmin,Li Ming

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 86-88

Abstract: sperm mortality significantly and Icr was not; When the concentration was 0.5 mg/mL,it is the lethal dose

Keywords： Ginsenoside CK     Icraiin     sperm     lethal dose    

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Numerical study on laminar flame speed of natural gas-carbon monoxide-air mixtures

Chen DONG, Qulan ZHOU, Qinxin ZHAO, Tongmo XU, Shi’en HUI

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 411-416 doi: 10.1007/s11705-010-0514-9

Abstract: The calculated laminar flame speeds of natural gas-carbon monoxide-air mixtures show a nonmonotonic increasing

Keywords： laminar flame speed     numerical study     nonmonotonic increasing trend    

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Development of a seismic design method based on response spectra for building structures

ZHOU Xiyuan, YU Ruifang

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 2,   Pages 129-141 doi: 10.1007/s11709-007-0014-2

Abstract: The assumption and problem of the mode-superposition response spectrum method in seismic design codeThe progresses on the mode superposition response spectrum theory are discussed.multiple-support seismic excitations and deducing corresponding method; 4) the approach for calculation of seismic responseof the non-classically damped system with overcritical damping and the calculation method of seismic response

Keywords： generalization     classical damping     mode-superposition response     calculation formula     damping theory    

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Confining pressure effect on dynamic response of high rockfill dam

Xuexing CAO, Yunlong HE, Kun XIONG,

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 1,   Pages 116-126 doi: 10.1007/s11709-010-0014-5

Abstract: A corresponding computational procedure was compiled and applied in the dynamic response analysis of

Keywords： confining pressure effect     high rockfill dam     dynamic response     Hardin-Drnevich constitutive model    

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Title Author Date Type Operation

U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen

Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang

Journal Article

Low-dose CT for lung cancer screening: opportunities and challenges

Hongbing Shen

Journal Article

Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the

Yue’e Dai, Dongxu Lei, Zhenghua Huang, Yan Yin, G. Allen Finley, Yunxia Zuo

Journal Article

Comparison of exogenous degrader-enhanced bioremediation with low-dose persulfate oxidation for polycyclic

Journal Article

Early assessment of the safety and immunogenicity of a third dose (booster) of COVID-19 immunization

Journal Article

An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Journal Article

Effect of chemical dose on phosphorus removal and membrane fouling control in a UCT-MBR

Guangrong Sun, Chuanyi Zhang, Wei Li, Limei Yuan, Shilong He, Liping Wang

Journal Article

radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes from an open-label, dose-escalation

Journal Article

Cancer and the environment: Filling knowledge gaps together

Linda S. BIRNBAUM PhD, DABT, ATS,

Journal Article

Venetoclax and low-dose cytarabine induced complete remission in a patient with high-risk acute myeloid

Bingshan Liu, Roshni Narurkar, Madhura Hanmantgad, Wahib Zafar, Yongping Song, Delong Liu

Journal Article

Efficient scheme of low-dose CT reconstruction using TV minimization with an adaptive stopping strategy

Yong DING, Tuo HU

Journal Article

The lethal dose test of Ginsenoside CK and Icraiin for sperm in vitro

Yu Hongliang,Chang Mingxiu,Cao Henghai,Bo Liwei,Yang Yongjun,Li Chongmin,Li Ming

Journal Article

Numerical study on laminar flame speed of natural gas-carbon monoxide-air mixtures

Chen DONG, Qulan ZHOU, Qinxin ZHAO, Tongmo XU, Shi’en HUI

Journal Article

Development of a seismic design method based on response spectra for building structures

ZHOU Xiyuan, YU Ruifang

Journal Article

Confining pressure effect on dynamic response of high rockfill dam

Xuexing CAO, Yunlong HE, Kun XIONG,

Journal Article